Symptoms of Depression   If you have experienced at least five of the following symptoms for at least two weeks, you may have clinical depression, and should seek help: Feeling sad or blue, unexplained crying spells Significant weight loss or weight gain Inability to sleep or excessive sleeping Agitation or irritability Fatigue or loss of energy Feelings of worthlessness or excessive guilt Inability to concentrate, indecisiveness Thoughts of death or suicide Lack of joy or not enjoying things previously enjoyed